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Tablet Presses

Looking to lower tableting service costs?

Natoli Tablet PressesNatoli’s line of efficient tablet presses combine remarkable tablet production, automation and dependability.

Whether your product requires a single-station, highly-efficient, manually operated tablet press, or a heavy-duty, high-output, automated tablet press, we have you covered with our lineup of specialized tablet presses.

No matter what tablet press you choose, when you buy from Natoli, you’ll receive:

  • Precise, consistent, and accurate tablets
  • Helpful customer service
  • Reliable technical support
  • Unmatched replacement part availability
  • And much more

Choose from our diverse line of specialized tablet presses to meet your specific tableting needs.

Research Tablet Presses

NP-RD10 & RD10A

NP-RD10A and NP-RD10*

  • Single station, semi-automatic tablet press
  • Ideal for pharmaceutical laboratory research and development
  • Significantly improves tablet uniformity and reduces trial-and-error
  • Easily meets tablet production requirements and specifications due to the independent control of both tablet hardness and weight
  • Fits well on bench top areas

*The NP-RD10 is a manually-operated model




  • Utilizes Standard TSM and EU “B”, “D”, “B2 Short Lowers”, “Core Rod”, “EK0” or “F” Tooling
  • Touch-screen Operator Interface
  • Programmable Parameters for Precompression Force Control, Compression Force Control, Dwell Time and Automatic Cycle Return
  • ½” Thick Lexan® Guards
  • Micro-Adjustable Depth of Fill
  • Extra Deep Fill Capacity Option
  • Automatic Ejection
  • CE Certified
  • 42 kN, 9500 lbs Compression
  • Multi-Layering Capabilities and More
  • Data Acquisition via Exportable CSV File
  • Mobile Press


Production Tablet Presses


Key Benefits:

  • High quality, low cost solution for tablet manufacturers in need of a medium-output rotary tablet press
  • Direct drive gears for decreased wear and slippage
  • cGMP and CE compliant
  • Designed, engineered and manufactured in the USA for quality and reliability
  • Complete spare parts inventory
SEE NP-155

NP-250 SeriesNP-250 Series

  • Single-sided D3 type tablet press
  • Pedestal-style, entry-level machine
  • Designed for use with 1” or 2” tablet tooling
  • Reliable, affordable tablet press designed to compress pharmaceutical, nutritional, veterinary, confectionery, and industrial tablets
  • Available with an automatic feeder
SEE NP-250

NP-400 SeriesNP-400 Series

Benefits and Features:

  • CE compliant
  • Touchscreen HMI
  • Standard main compression force monitoring
  • Automatic weight control
  • Tool-less zero clearance forced feeder
  • Hardened steel die table
  • Dosing tunnel VPN router for remote technical support
SEE NP-400

NP-500 SeriesNP-500 Series

  • Heavy-duty, double-sided rotary tablet press
  • Ideal for high compression ratio products
  • Designed to compress tablets that need extra fill and extended dwell time
  • Comes in semi-automatic and automatic models
  • Known for its tablet production, automation, and dependability
  • Significantly lower servicing costs makes it economically efficient
  • Enhanced hopper design improves granulation control
SEE NP-500

If you’re looking for tablet presses, we’re your best choice!  From tablet presses and tablet press replacement parts, to world-class customer service, Natoli is the undisputed leader in the tablet tooling industry.  So choose the experience and dependability of Natoli Engineering Company to provide a solution.


Tablet Press