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Anti-Sticking: A Case Study

Thursday, 24 October 2019 by

Are You Paying for Your Problem? What price do you put on something so integral to your product’s success? At Natoli, our goal is to support you in making a quality solid-dose product efficiently. Recently, a pharmaceutical company asked for our help to solve a sticking problem. The issue began shortly after start-up, despite the use of specialty coated

The Natoli Engineering Service Center in Cypress, California held yet another successful, sold-out training course in May of 2019. Attendees, a mix of R&D and technical operators/technicians, were instructed by Natoli’s tableting experts while working hands-on with equipment to design, formulate, and compress tablets. Cannabis tablets are garnering attention in both the recreational and medical industries

Natoli Engineering headquarters, located in St. Charles, Missouri, will be offering the Basics of Tablet Manufacturing and Troubleshooting course June 11-13th. This course is anything but basic and ensures that tablet press operators, R&D, technicians, supervisors, and others within the field understand the entire process of tablet manufacturing. Training sessions are instructed by Natoli’s knowledgeable

Tablet Compression scale-up, coating, and formulation development

Natoli Scientific will be holding a two-day training course on tablet compression scale-up, coating, and formulation development June 4 & 5 featuring guest presenters from MilliporeSigma. The course is taught by industry experts who provide comprehensive lectures and hands-on training experiences to provide you with a comprehensive and immersive learning opportunity. If you work in

Natoli Tablet Compression Resource Training and Service Center in Szczecin Poland, is holding a comprehensive two-day training course June 11 & 12. Join Hans Eirik Forsjord, Natoli Technical Training Expert, and Grzegorz Grzybowski, Executive Manager at Natoli Poland, for in-depth training on everything from basics to best practices for optimum tablet production. If you’re looking

Natoli Engineering hosts multiple training courses throughout the year to provide tablet manufacturers with an invaluable opportunity to learn more about tablet manufacturing processes and troubleshooting methods.  Natoli recently hosted attendees from across the U.S. at our headquarters, located in Saint Charles, Missouri, for this three-day training event. Course topics included: tablet press setup and

We’re quickly approaching one of the largest pharmaceutical, biotechnology, and medical device development and manufacturing tradeshows in the U.S; Interphex is right around the corner! With well over 10,000 attendees from around the globe, we understand how exciting and busy the tradeshow floor can be. Natoli Engineering will be hosting a hospitality suite on Wednesday,

Natoli Scientific recently held their first training course of 2019 at the R&D Laboratory in Telford, Pennsylvania. Natoli technical trainers were joined by industry-leading experts for the three-day course on Tablet Development and Scale-up. Attendees were provided instruction on the tablet development process and scale-up methodology within a unique classroom setting and laboratory environment. The

Rushing A Product to Market Can Yield Some Expensive and Painful Lessons When scaling a new drug formulation from development into manufacturing, there is often a reality check regarding process scale-up and formulation performance at production levels. Problems with capping/lamination and sticking/picking are often first realized when a formulation is introduced to a level of

The number one reason for tablet press failure is lack of tooling cleanliness. Dirty tooling may cause binding, which can damage tooling and tablet presses. Keeping tools clean can decrease premature tool wear and allow lubrication to be more effective as well as reduce the possibility of product cross-contamination. Additionally, clean tooling is critical to

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