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This article originally ran in the October 2018 issue of European Pharmaceutical Manufacturer magazine. By Jonathan Gaik, Natoli Scientific Tablet formulation development is a stylised process. Each formulator uses their own methodology. Some use the systematic Design of Experiments (DOE) approach, some test one variable at a time, and many use a combination of the two. However, all

Natoli Engineering participated as an exhibitor at the International Society for Pharmaceutical Engineering Annual Conference and Expo in Philadelphia, Pennsylvania, November 4-6.  ISPE attendees had the opportunity to visit with members of the Natoli Scientific team and learn how Natoli can solve tablet compression challenges during research and development and manufacturing.  The International Society for

In the October 22, 2018, issue of Solid Dose Digest, a reader asked, “I need tablet compression training. How do I decide which course is right for me?” Natoli Scientific Director Jonathan Gaik answered: Tablet compression is complicated, and most who work in the industry learn on the job, but a growing number of options

Natoli Engineering hosted another sold-out class for its fall of Tablet Manufacturing & Troubleshooting training. Thirty-five participants visited our Technical Training Center in St. Charles, Missouri, to attend the course on October 23-25, 2018. Attendees represented a wide range of industries, including pharmaceuticals, biotech, veterinary, nutritionals, confectionery, pyrotechnics, dietary supplements, cleaning ingredients, and snacks. They also covered a variety

Sticking and picking are ubiquitous problems in tablet manufacturing and generally arise from either formulation or tablet design inadequacies. Sticking occurs when formulation granules stick to the face of the punch cup. Formulation sticking in the letters and characters of punch embossing is typically referred to as picking. Both result in tablet defects and lower

Robert Sedlock, Director of Technical Training & Development at Natoli Scientific, taught a module on tablet compaction for a short course at the University of Maryland School of Pharmacy. The course, Tablets & Capsules Hands-On Short Course, took place October 15-19, 2018. Robert’s lecture taught course participants about powder compression, tablet press operation, test methods for formulation development, and compaction

Natoli Scientific’s new Telford, Pennsylvania, R&D laboratory opened its doors with the inaugural “Formulation Development, Scale-up, and Intro to Microtabs” training October 8-10, 2018. Seventeen attendees from the pharma, specialty chemicals, nutritional supplements, and pyrotechnics industries helped us kick off activities in our new facility. Taught by industry-leading experts, our attendees learned new approaches to formulation

Natoli Engineering is excited to be exhibiting at the upcoming SupplySide West 2018! The trade show will take place November 6-10, 2018, at Mandalay Bay in Las Vegas. We will showcase our extensive portfolio of tableting and encapsulation products and services that solve challenges with troublesome and sticky formulations commonly found in cannabis and nutraceutical products. We’ll be offering

Natoli Engineering exhibited at the Maghreb Pharma Expo 2018 October 17-19 in Algiers, Algeria. Many attendees from Algerian, MENA, and multinational pharmaceutical companies stopped by our booth to talk about their tablet compression tooling needs. Maghreb Pharma Expo is an annual event created to follow the development of local Algerian pharmaceutical manufacturing investments. It has become a regional event

Natoli Engineering and the industry’s foremost subject matter experts are joining together for a new and unique hands-on training and troubleshooting panel discussion. The inaugural training event is being help October 8-10, 2018, at our new Natoli Scientific Research & Development Laboratory in Telford, Pennsylvania. “Tablet Development, Scale-Up, and Intro to Microtabs” provides comprehensive insight

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