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This breakthrough publication, authored by leading research pharmacist, Dr. Patrick C. Okoye, with a forward by Dale Natoli, President of Natoli Engineering, shines new light on the relationship between polymorphism in magnesium stearate and its impact on the tablet lubrication process and drug dissolution. Magnesium stearate (MgSt) is widely used in cosmetic, food and pharmaceutical

Solid Dose Outsourcing Trends

Tuesday, 18 October 2016 by

This post shares content from an article in Contract Pharma. Click here for the full article. The pharmaceutical industry has seen a number of changes in the more than 40 years Natoli Engineering has been a major manufacturer of tablet compression tooling. From medical advances to the continued growing trend to outsource pharmaceutical manufacturing, the solid dose

This article originally published in Tablets and Capsules’ “Solid Dose Digest” sent July 25, 2016. Industry experts have long debated the best tooling for tablet manufacturing. To understand why their opinions differ, you must first understand the history of the punch. In this edition of the column, I show that the standard head flat has

For a number of years the buzz around continuous manufacturing as the next big leap in pharmaceutical manufacturing has grown. From companies looking for greater efficiency in their processes to governmental regulations enacting changes, the tableting industry has been working hard on solving this puzzle. While the theories of how a company can enact these

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