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Rushing A Product to Market Can Yield Some Expensive and Painful Lessons When scaling a new drug formulation from development into manufacturing, there is often a reality check regarding process scale-up and formulation performance at production levels. Problems with capping/lamination and sticking/picking are often first realized when a formulation is introduced to a level of

The number one reason for tablet press failure is lack of tooling cleanliness. Dirty tooling may cause binding, which can damage tooling and tablet presses. Keeping tools clean can decrease premature tool wear and allow lubrication to be more effective as well as reduce the possibility of product cross-contamination. Additionally, clean tooling is critical to

Maximizing Your Tooling ROI

Thursday, 21 February 2019 by

Tablet compression tooling is a considerable investment for your company. Quality tooling and a proper maintenance program are integral to producing high-quality tablets efficiently. Polishing and refurbishing are two of the surest and most inexpensive ways to maintain tablet quality, reduce operating costs, and yield the full ROI potential of your tooling. Punches and dies will

Training Class Room

Natoli Engineering has announced the 2019 dates of the Basics of Tablet Manufacturing & Troubleshooting course held at Natoli’s Technical Training Center in St. Charles, Missouri: March 12-14, June 11-13, August 13-15 and October 22-24. This popular three-day training course enhances attendees’ knowledge of tablet press setup, maintenance and operation, tablet design, tooling and press maintenance

First impressions are everything, especially for pharmaceutical, nutritional, and confectionery tablets. Discriminating consumers may decide whether they will be repeat customers based on a tablet’s appearance and their experience. That’s why tablet design should not be overlooked or taken for granted. Much too often in our industry, we see poor tablet design holding back companies. Don’t

Natoli Engineering Company, Inc.’s TabletCAD® web-based tablet design software is a unique and complimentary online service that offers the convenience of designing tablets in-house with real-time validation. TabletCAD® links tablet designs directly to the manufacturing process so tooling will be shaped precisely to the models. An intuitive user interface guides the design process with helpful

Natoli Engineering Company, Inc., the global leader in tablet compression tooling, custom engineers and crafts a wide range of precision multi-tip tooling in various configurations to customers’ exact specifications. Multi-tip tooling significantly increases tablet production without adding a new tablet press or additional space and labor. It also: Reduces press run time with higher production

Natoli Scientific was founded to research new formulation techniques and tablet compression technology. We combine our four decades of experience with a network of university, consultant, and resident resources to investigate problems and offer our customers unique solutions to their product formulation and tooling requirements. Using the correct tablet tooling selection, tool steel, tool coating,

Tired of the Guesswork?

Monday, 14 August 2017 by
Natoli Engineering helps solve tablet and tooling issues.

You’ve tried every trick in the book and nothing seems to fix your sticking and picking issues. At Natoli Engineering, we’ve done our homework. Our tablet and tooling experts find and fix tableting troubles every day. Using real-world knowledge and technical data, we’ll analyze issues to create real solutions for your problems. Whether you need

Dust cups are a low-cost solution that keep excess lubrication out of tablets, and bellows help reduce issues like tool binding by reducing friction by keeping formulation off tools. As tip-mounted dust cups require you to cut out a hole to install on punches, Natoli has developed our Dust Cup Cutting Tool to make this

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