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NP-P20A

Designed for Small Scale Production

Natoli Engineering’s NP-P20A single-station hydraulic tablet press is a favorite for the production of injectable micropellets and for marginal formulations requiring deep-fill. The NP-P20A meets the FDA’s requirements for batch reporting and secure data management under CFR 21 Part 11 compliance.

Press Features:

  • Natoli AIM™ ProPlus control system software
  • Easy-to-use menu-driven operation
  • Intuitive 12″ HMI touchscreen
  • Mobile press with four casters
  • Utilizes standard TSM and EU B, D, core rod, deep-fill, and multi-tip tooling. Tooling can be keyed or not keyed
  • Programmable parameters for pre- and main compression force control
  • Completely enclosed guard system
  • Autodosing feature adjusts dosing to maintain compression force with product granulation density changes
  • Automatic ejection

Optional Features:

  • Deep-fill B and D tooling option increases B or D tooling maximum depth of fill from 12.7 mm to 34.9 mm using special deep-fill tooling
  • Core rod B and D tooling
  • Large tablets with a major axis up to 50 mm can be produced in standard and unique shapes

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Natoli AIM™ProPlus Control System:

Industry-leading Natoli AIM™ ProPlus control system software provides all the reporting and features of a full-size production rotary tablet press – modified to a single-station configuration.

Audit Trail Module:

  • Records all critical setting changes during batch production.

Recipe Module:

  • Reduces set-up time by storing product recipes in a secure database.

Batch Reporting Module:

  • Records and stores all batch records, alarms, errors, stops and starts. This information can be extracted to a USB drive or automatically saved to a secure network drive.

Security Module:

  • Has five levels of security based on job function. Authentication and accessibility to different modules can be managed at the console or from a remote connection. Optional authentication using an HID badge can be added.

Remote Module:

  • Provides a secure connection so settings and critical production data can be monitored remotely from a desktop PC. Natoli engineers can troubleshoot issues, monitor performance, and install software upgrades remotely after hours if required.

Formulation Fill Options:

Standard Fill: Produces standard-sized tablets from formulations that are capable of consistently filling the dies.
Shaker Fill: Enables injectable micropellets to be produced vertically even with product formulations whose characteristics will not fill the die consistently.
Deep-Fill: Provides the fill depth to make very thick tablets and injectable micropellets vertically even in higher dosages.
Double-Fill: Produces tablets that require more fill depth than allowed with the deep-fill option.
Pre-compression: Eliminates air entrapment to prevent capping and lamination and can be run simultaneously with other operating modes.

Key Benefits:

  • Consistent Pellet/Tablet Thickness: Both upper and lower punch positions are adjusted at maximum compression to ensure consistency of tablet/pellet thickness, a critical dimension for injectable therapies.
  • Rejects Defective Tablets: User-programmable tablet rejection system automatically identifies and rejects tablets based on compression force changes and the position of the upper and lower punches at maximum compression.
  • Consistent Weight Control: Feeder paddle speed and fill time of the die are adjustable, allowing even hard-to-tablet products to be produced at a consistent weight.

Standard

~120Tablets Per Hour

  • PUNCH TYPE:
    EU 19, 1″/TSM B, D
  • MAX. ROUND DIAMETER:
    16.0—23.8mm (0.6299—0.9370″)
  • MAX. DEPTH OF FILL:
    17.5—22.2mm (0.3437—0.8740″)
  • SHAPED MAJOR DIMENSION:
    16.0—25.4mm (0.6299—1.00″)
  • MAX. PRE-COMPRESSION:
    42 kN / 9,500 lbs
  • MAX. MAIN COMPRESSION:
    42 kN / 9,500 lbs

Deep Fill

~120Tablets Per Hour

  • PUNCH TYPE:
    Deep Fill B/D
  • MAX. ROUND DIAMETER:
    17.5—23.8mm (0.6875—0.9370″)
  • MAX. DEPTH OF FILL:
    12.7—34.9mm (0.5000—1.3740″)
  • SHAPED MAJOR DIMENSION:
    19.1—25.4mm (0.7519—1.00″)
  • MAX. PRE-COMPRESSION:
    42 kN / 9,500 lbs
  • MAX. MAIN COMPRESSION:
    42 kN / 9,500 lbs

QUOTE REQUEST

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