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Anti-Sticking: A Case Study

Thursday, 24 October 2019 by

Are You Paying for Your Problem? What price do you put on something so integral to your product’s success? At Natoli, our goal is to support you in making a quality solid-dose product efficiently. Recently, a pharmaceutical company asked for our help to solve a sticking problem. The issue began shortly after start-up, despite the use of specialty coated

We’re quickly approaching one of the largest pharmaceutical, biotechnology, and medical device development and manufacturing tradeshows in the U.S; Interphex is right around the corner! With well over 10,000 attendees from around the globe, we understand how exciting and busy the tradeshow floor can be. Natoli Engineering will be hosting a hospitality suite on Wednesday,

Rushing A Product to Market Can Yield Some Expensive and Painful Lessons When scaling a new drug formulation from development into manufacturing, there is often a reality check regarding process scale-up and formulation performance at production levels. Problems with capping/lamination and sticking/picking are often first realized when a formulation is introduced to a level of

The number one reason for tablet press failure is lack of tooling cleanliness. Dirty tooling may cause binding, which can damage tooling and tablet presses. Keeping tools clean can decrease premature tool wear and allow lubrication to be more effective as well as reduce the possibility of product cross-contamination. Additionally, clean tooling is critical to

Learn How to Eliminate Tablet Defects and Prolong Tooling Life Join Natoli Engineering at our Long Island TCR Service Center for a FREE, all-day Compression Session on Thursday, February 21st to learn how you can eliminate tablet defects, increase tooling life, and reduce costs. If your tooling has lost its luster or wear patterns are

Sticking and picking are ubiquitous problems in tablet manufacturing and generally arise from either formulation or tablet design inadequacies. Sticking occurs when formulation granules stick to the face of the punch cup. Formulation sticking in the letters and characters of punch embossing is typically referred to as picking. Both result in tablet defects and lower

Natoli Engineering and the industry’s foremost subject matter experts are joining together for a new and unique hands-on training and troubleshooting panel discussion. The inaugural training event is being help October 8-10, 2018, at our new Natoli Scientific Research & Development Laboratory in Telford, Pennsylvania. “Tablet Development, Scale-Up, and Intro to Microtabs” provides comprehensive insight

Natoli Engineering is excited to be exhibiting at the upcoming PACK EXPO International! The trade show will take place October 14-17, 2018, at McCormick Place in Chicago. Use code 75G95 when you register for the show and get complimentary registration courtesy of your friends at Natoli Engineering! Attendees who visit us at Booth W-637 will have a chance to see

Natoli Engineering unveiled innovative new products at the ACHEMA Congress, the most important trade show for the process industry, held June 11-15 in Frankfurt, Germany. Our exhibit space was crowded with visitors who wanted to learn more about our tableting solutions. The biggest draw to the Natoli booth was our Quick-Release™ Tooling. Quick-Release™ Tooling is a game-changer

Natoli Engineering hosted a full class of 32 attendees at its recent technical training course. Participants from as close as St. Louis and as far away as Colombia attended Natoli’s Technical Training Center in St. Charles, Missouri, for the Basics of Tablet Manufacturing & Troubleshooting training May 22-24, 2018. Attendees of this training class were from a variety of industries, including

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