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Natoli Scientific

Close Up of Pills with Natoli Engineering Logo from Tablet Compression Machines

From product concept to trouble-shooting, Natoli Scientific experts offer solutions and recommendations.

Technical Training

Tablet Press Calibration Services

Data Acquisition Systems

Formulation Development

Analytical Services

Tooling Recommendations


Natoli Careers

Workers at Natoli Engineering Graphic

Natoli offers more than just a job, a career! Below are some of our current opportunities, click on the button below to see every available position.

All Shifts – CNC Machinist – St. Charles, MO

Mechanical Engineer – St. Charles, MO

Facility Maintenance – St. Charles, MO

Territory Sales Manager – Midwest – St. Charles, MO

Service Tech – St. Charles, MO

Mechanical Drafter – St. Charles, MO

HR Generalist – St. Charles, MO

About Natoli

Natoli Engineering Company, Inc., is the world-renowned leader in tablet compression tooling. But we are far more. Founded on the uncompromising principle to manufacture and deliver the highest quality products at a fair price with exceptional customer service, Natoli continues to build on a half century of innovation and industry leadership.



Close Up of Tablet Press Punch Tips


Improperly torqued dies can crack, split or “pop-up” resulting in damage to the feed frame and tooling. This can cause thousands of dollars worth of repair costs, unsafe working conditions, unwanted downtime and a significant reduction in product output. Using preset torque wrenches will ensure dies are torqued to the exact specifications listed in the tablet press manual.


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Thank you very much for all of the help and patience with these sets of tooling, I know it has been difficult at some points with a lot of changes along the way. All of your work is much appreciated.

- Pharmaceutical and Biopharmaceutical Company