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Easily Solve Formulation and Scale-up Challenges

NP-RD30-PhotographNatoli Engineering is quickly becoming the leader in R&D tablet presses with this next-generation rotary tablet press. Designed to help solve formulation and scale-up challenges, the NP-RD30 rotary R&D tablet press replicates the design and functionality of a production press. The turret velocity of the NP-RD30 can reach that of production presses, meaning dwell time can be more accurately established during research and development. Five rolling casters allow for easy mobility.

NP-RD30 Features:

  • Natoli AIM™ Plus data acquisition and analytical software
  • User-friendly interface displayed on a 21″ HMI touchscreen
  • USB port for easy data transfer
  • 21 CFR Part 11-compliant
  • Identical pre- and main compression roll diameter
  • Pre- and main compression, ejection, and take-off force monitoring
  • Independent overload for pre- and main compression
  • Automatic and dosing weight control
  • Patented Fast-Fill cam design
  • Integrated dual vacuum system
  • Standard batch reporting
  • Error and alarm tracking and reporting
  • Built-in calibration tool
  • Upper and lower punch seals
  • Adjustable lower punch retainers with quick-release tab
  • Containment-ready separate compression zone
  • Powder recirculation system
  • Dual-paddle, variable-speed feeder design
  • Optional security and HID badge capabilities allow login based on job responsibility

While designed to meet the needs of research and development teams, the NP-RD30 could be used as a small tablet production press.

Download-Brochure-NP-RD30

Get your product to market faster with the data acquisition, analysis, and scalability features of the NP-RD30!

The NP-RD30’s integrated AIM™Plus data acquisition and analytical software is designed to ease formulation and process development and minimize production issues during scale-up.

Natoli AIM™Plus Capabilities Speed Tablet Scale-up:

Data Acquisition

  • Monitors and records peak values for critical events during tableting process

Data Library

  • Includes database of production press specifications for most press models and manufacturers
  • Provides accurate scale-up data for exact production press using preloaded information and R&D data input

Dwell Time Assessment

  • Establishes ideal production dwell time for varying tablet design specifications and tooling head flats

Tangential Velocity Assessment

  • Determines tangential velocity using pitch circle diameter and RPM ranges
  • Analyzes dwell and compaction time at varying turret speeds
  • Provides manufacturers with live R&D data normalized for their specific production press

Compaction Time Assessment

  • Analyzes tangential velocity, compression roller diameter, and punch head configuration to calculate compaction time parameters needed
    in production

AIM™ Plus for the NP-RD30:

  • Provides tablet press scalability parameters
  • Calculates tensile strength for round, convex, and oblong tablets
  • Quickly measures and evaluates tablet formulations and properties
  • Provides projected data from formulation changes
  • Reduces trial and error
  • Evaluates compaction properties of APIs and potential formulations
  • Measures and reports data for tabletability, compactibility, compressibility, and strain rate profiles
  • Effectively optimizes lubrication levels with ejection/compression profiles

AIM-Plus-RD30-Screenshot-wDATA

The Natoli AIM™ Plus main data screen provides an easy-to-interpret visual interface for quick assessment of formulation performance. Operator can control press speed and quickly view minimum and maximum pre-compression, compression and ejection forces in real time.

Tablet Press Specifications for the NP-RD30:

4+4 STATION

~40-400Tablets Per Minute

  • PUNCH TYPE:
    EU 19/EU D/TSM B,D
  • DIE TYPE:
    B or D
  • MAXIMUM TABLET DEPTH OF FILL:
    20—22mm (.787—.866″)
  • MAXIMUM ROUND TABLET DIAMETER:
    17.5—23.8mm (.6875—.9375″)
  • SHAPED MAJOR DIMENSION:
    19.0—25.4mm  (.7500—1.000″)
  • PRE- AND MAIN UPPER PUNCH PENETRATION:
    0—6mm
  • PRE-COMPRESSION FORCE:
    10kN
  • MAIN COMPRESSION FORCE:
    60kN
  • PITCH CIRCLE DIAMETER:
    200mm
  • DWELL TIME RANGE:
    91—9.1ms
  • TANGENTIAL VELOCITY RANGE:
    105—1047mm/sec

8 STATION

~80-800Tablets Per Minute

  • PUNCH TYPE:
    EU D/TSM D
  • DIE TYPE:
    D
  • MAXIMUM TABLET DEPTH OF FILL:
    22mm (.866″)
  • MAXIMUM ROUND TABLET DIAMETER:
    23.8mm (.9375″)
  • SHAPED MAJOR DIMENSION:
    25.4mm (1.000″)
  • PRE- AND MAIN UPPER PUNCH PENETRATION:
    0—6mm
  • PRE-COMPRESSION FORCE:
    10kN
  • MAIN COMPRESSION FORCE:
    60kN
  • PITCH CIRCLE DIAMETER:
    200mm
  • DWELL TIME RANGE:
    91—9.1ms
  • TANGENTIAL VELOCITY RANGE:
    105—1047mm/sec

10 STATION

~100-1,000Tablets Per Minute

  • PUNCH TYPE:
    EU 19/TSM B
  • DIE TYPE:
    B
  • MAXIMUM TABLET DEPTH OF FILL:
    20mm (.787″)
  • MAXIMUM ROUND TABLET DIAMETER:
    17.5mm (.6875″)
  • SHAPED MAJOR DIMENSION:
    19.0mm (.7500″)
  • PRE- AND MAIN UPPER PUNCH PENETRATION:
    0—6mm
  • PRE-COMPRESSION FORCE:
    10kN
  • MAIN COMPRESSION FORCE:
    60kN
  • PITCH CIRCLE DIAMETER:
    200mm
  • DWELL TIME RANGE:
    91—9.1ms
  • TANGENTIAL VELOCITY RANGE:
    105—1047mm/sec

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