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Setting a New Benchmark for Ease of Operation

The NP-255 is a robust tablet press that was built to meet even the most demanding needs of the mid-sized tableting industry. The press has features and options designed to increase production, improve tablet quality, reduce waste, and set a new benchmark for ease of operation. Designed, engineered, and manufactured in the USA, this unique machine has a maximum production speed of 192,000 tablets per hour.

With a hardened steel die table, a gravity feeder that is interchangeable with a two-paddle forced feeder, and our industry-leading intuitive Natoli AIM™ ProPlus control system, the NP-255 is the new standard for value in the mid-sized tableting industry.

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  • Standard TSM and EU B, D, or BB tooling
  • Intuitive AIM™ control system provides operation feedback to help maintain tablet quality and improve productivity
  • Continuously lubricated punches, cams, and turret to help eliminate wear, reduce heat, and minimize product sticking issues
  • Tablet weight, thickness, and hardness adjustments can be made as needed during production
  • Completely segregated compression and mechanical zones
  • Punch barrels and die table are vacuumed during production to eliminate build up and reduce change over time
  • Upper and lower punch guides have soft seals to reduce punch binding and heat in the punches, and contain the product granulation
  • Reduced product loss with our specially designed feeder and powder recirculation system
  • Upper and lower cam track guards keep cams cleaner to reduce heat, wear, and increased tooling life
  • Lower punch retainers to help maintain consistent tablet weight
  • Direct drive gears for decreased wear and slippage
  • Turret mounted with upper and lower tapered bearing
  • cGMP- and CE-compliant

  • Instrumented force monitoring
  • Combination caster/levelers for easy mobility and setup
  • Dual-paddle power rotary forced feeder
  • Tablet reject chute
  • 3VT System
  • Hopper vibration unit

Key Benefits:

  • The NP-255 boasts features essential for successful mid-sized tableting without the full-scale price. Ready to take on your manufacturing needs, the NP-255 is easy to operate and utilizes Natoli AIM™ ProPlus Control System. Proudly designed, engineered, and manufactured in the USA, the NP-255 is the new standard for value in the mid-sized tableting industry.
  • AUTO-LUBRICATED PUNCH GUIDES – Reduce wear and heat build-up, minimizing sticking and binding.
  • EASY ACCESS TO DOSING, COMPRESSION & OVERLOAD SETTINGS – Allows press operators to adjust settings while press is in production.
  • Push-button, Self-adjusting Lower Punch Retainers shorten installation time and reduce tooling and cam wear.

Natoli NP-255 Tablet Press Specifications:

22 Station 28 Station 32 Station
Tooling Sizes
Punch Type EU 1″ / TSM D / MDT-25 EU 19 / TSM B / MDT-19 EU 19 / TSM B / MDT-19
Die Type D B BB
Tablet Capacities
Max. Tablet Depth of Fill 20.6 mm (0.8125″) 17.5 mm (0.6875″) 17.5 mm (0.6875″)
Max. Round Tablet Diameter 23.8 mm (0.9375″) 17.5 mm (0.6875″) 16.0 mm (0.6250″)
Shaped Major Diameter 25.4 mm (1.00″) 19.0 mm (0.7500″) 16.0 mm (0.6250″)
Main Upper Punch Penetration 0-6.35 mm
Operating Forces
Max Main Compression Force 90kN
Pitch Circle Diameter 292 mm
Tablet Rates
Turret Speed 10-100 RPM
Tablet Rate Per Hour 13,200-132,000 16,800-168,000 19,200-192,000

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Thank you so much for getting the tooling done so quickly.  As I was telling my client, I had a great relationship with Natoli in the past at my previous employer and Natoli will always go above and beyond to try to help the client out but even I was surprised that you could turn around this order so quickly.  From our management, we really appreciated Natoli being able to process the tooling in an expedited manner!!!!

- a Pharmaceutical Company