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Natoli Acquires AIM Software, Carlisle Precision Machining

Natoli Engineering is beginning 2018 with exciting developments! First, we are proud to announce that we have acquired AIM™ Data Acquisition and Analytical Software from Measurement Control Corporation (MCC). Easy-to-use, Windows-based AIM™ Data Acquisition and Analytical Software facilitates and speeds tablet and capsule research and development and manufacturing by the pharmaceutical, nutraceutical, confectionery, and veterinary… Read More

Which USP Chapter is the Most Important for Encapsulation?

In the tablet compression industry, we widely regarded USP Chapter <1062> as the one chapter that any R&D Scientist should be familiar with as they develop new formulations. This Chapter describes the relationship between a tablet’s compactibility, compressibility, tabletability, and manufacturability. But what about encapsulation? Capsule filling machines differ greatly from rotary tablet presses. There… Read More

Visit Natoli at ACHEMA 2022

For the first time in four years, Natoli Engineering will be an exhibitor at the upcoming ACHEMA 2022 trade show! The highly anticipated event will take place August 22nd to 26th in Frankfurt am Mein, Germany. We’ll be showing off our full lineup of products, services, and research that helps you turn good products into… Read More

Another Sold-Out Class for Tablet Manufacturing

Natoli Engineering hosted another sold-out class for its fall of Tablet Manufacturing & Troubleshooting training. Thirty-five participants visited our Technical Training Center in St. Charles, Missouri, to attend the course on October 23-25, 2018. Attendees represented a wide range of industries, including pharmaceuticals, biotech, veterinary, nutritionals, confectionery, pyrotechnics, dietary supplements, cleaning ingredients, and snacks. They also covered… Read More

Maximizing Tooling Life

We are passionate about training scientists and operators in the tablet compression industry. We love hosting them at our Technical Centers, but we are also honored when our customers invite us into their facilities for on-site training as well. Such was the case when our customer asked our tooling experts to train their staff. This… Read More

A Case Study in Tablet Tooling Steel Quality

Natoli Engineering’s Metallurgy Department performs steel quality control on the tablet tooling that we send to our customers. However, they can also help to combat issues that put you behind in production. This analysis can help you troubleshoot tooling issues such as wear, breakage, corrosion, and fatigue. So, when customers send us their tooling (regardless… Read More

Impact of Punch Cup Depths on USP <1062> Profiles and Capping Index

USP <1062> tablet characterization is one of the most integral chapters to understanding the tablet characterization process; it helps to understand the compactibility, tabletability, and compressibility of the material. USP <1062> profiles are impacted by any adjustments to the material and tablet tooling. In the present study, Natoli has mainly focused on the impact of… Read More

Natoli’s G.A.S. Program Helps Employees Reduce Cost of Commute

Inflation. Bear markets. International conflicts. Fuel supply shortages. In today’s economic climate, we could cut the tension with a plastic knife. Those who are employed are facing a cost-of-living crisis, while their forward-thinking employers face an opportunity. On the tail of the Great Resignation, companies are looking for unique ways to show employees they can… Read More


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The training, factory staff and instruction completely exceeded all expectations. I would come back anytime; easily one of the Top 10, if not Top 5, companies I have visited with. I spoke with Dale about what a great company Natoli is.

- Animal Health Company