skip to main content

Natoli Inspires a New Generation of Workers

Natoli hosted a class of local high school students today at our global headquarters in St. Charles, MO. A cohort of approximately 30 students from the Center for Advanced Professional Studies (CAPS) toured our facility, led by training instructors Dave Holleran, Bill Turner, and Doug Kirsch, learning the basics of tooling manufacturing. The goal of… Read More

Natoli to Host Social Mixer After 2022 Interphex Conference

Come have a drink on us while savoring a one-of-a-kind view of Times Square in the heart of New York City! On the evening of Wednesday, May 25th, 2022, Natoli will host a casual mixer for attendees of the Interphex conference. This event will provide an opportunity for industry professionals to socialize in a relaxed… Read More

Natoli Attends 2022 Excipient World Conference & Expo

The 2022 Excipient World Conference & Expo, held in Kissimmee, Florida was a success! This was the conference’s first production since the global pandemic in 2020, which required the expo to be cancelled. Natoli returned to the conference in full force with a poster presentation on the impact of punch cup depths on USP <1062> Profiles… Read More

Compression pressure, tensile strength, and solid fraction diagram

Natoli Hosts First-of-its-Kind Training Seminar on USP <1062>

  Five years ago, the U.S. Pharmacopeia (USP) published a general chapter <1062> on Tablet Compression Characterization. In simplest terms, USP general chapter <1062> provides direction for best practices as they relate to tablet compression test procedures. Despite the half-decade timeframe, very few companies have made an intentional effort to instruct R&D scientists on how… Read More

Powder Rheology: Gateway For Tablet Sticking Insights

Authors: Devang Patel, Kerry Cruz, Robert Sedlock, Rahul Haware A tablet is the product of the right marriage between pharmaceutical materials and manufacturing conditions. Proper pharmaceutical blend properties are a major contributor of this success. Though pharmaceutical tablets have enjoyed their place on the pharmacy shelves for centuries, their development is prevalently based on trial… Read More

Natoli Welcomes Guests To Sip, Savor, and Socialize

Natoli Engineering once again hosted a business after hours event during the Interphex conference in New York City. Dale Natoli and fellow employees welcomed guests from the pharma and biotech industry for an evening to “Sip. Savor. Socialize.” The gathering was held Oct. 20, 2021 at the Moxy Hotel, beneath the Manhattan lights of Times… Read More

Rotary Tablet Press Cycle

Powder Die Filling Is Essential To Produce Quality Tablets

  by Robert Sedlock, Director, Natoli Scientific The tablet manufacturing process has many challenges. An understanding of the steps leading up to the final compressed tablet is crucial to the task of producing a high-quality tablet. The final tablet weight is a direct response of the volumetric filling of the die during the tableting process. Thus,… Read More


For quarterly tooling tips, special deals, industry news, and more!

I would like to pass on sincere appreciation to you and your team for 3 days turn around (sic). Very quick delivery and excellent service!

- Pharmaceutical Services Company