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Impact of Punch Cup Depths on USP <1062> Profiles and Capping Index

USP <1062> tablet characterization is one of the most integral chapters to understanding the tablet characterization process; it helps to understand the compactibility, tabletability, and compressibility of the material. USP <1062> profiles are impacted by any adjustments to the material and tablet tooling. In the present study, Natoli has mainly focused on the impact of… Read More

Impact of Punch Cup Depths on USP Graph

Closing The ‘Knowing-Doing’ Gap In R&D Using USP <1062> Data

One of the most rewarding things about being a science technician is being able to easily measure your impact. And for many in the pharmaceutical industry today, measuring this impact begins with analytics. As an R&D scientist, accessing your analytics is essential to determining whether your formulation’s purpose can be realized, i.e. if the product’s… Read More

Powder Rheology: Gateway For Tablet Sticking Insights

A tablet is the product of the right marriage between pharmaceutical materials and manufacturing conditions. Proper pharmaceutical blend properties are a major contributor of this success. Though pharmaceutical tablets have enjoyed their place on the pharmacy shelves for centuries, their development is prevalently based on trial and error instead of a robust scientific approach. This… Read More

Rotary Tablet Press Cycle

Powder Die Filling Is Essential To Produce Quality Tablets

  by Robert Sedlock, Director, Natoli Scientific The tablet manufacturing process has many challenges. An understanding of the steps leading up to the final compressed tablet is crucial to the task of producing a high-quality tablet. The final tablet weight is a direct response of the volumetric filling of the die during the tableting process. Thus,… Read More

Close Up Of Encapsulated Pills Graphic

Solving Encapsulation Issues Caused by Sticky Formulations

During capsule production, are you noticing capsule defects such as body dents or cap dents? Are you seeing nicks and scratches on dosing bores or rounded noses and/or deep scratches tamping pins? A sticky product formulation might be the culprit! We asked our encapsulation expert, Jon Carlisle, to put together a guide that will walk… Read More

Tablet Tooling Nutraceutical Products

Manufacturers use tablet presses to produce a variety of products, such as pharmaceuticals, nutraceuticals, veterinary products, confectionary products, and industrial tablets. Each industry faces unique challenges depending on the properties inherent to the formulations that industry uses. A variety of steel types and coatings, tool-design modifications and options, and tablet designs can work together to… Read More

tablet press replacement parts

Non-OEM Parts – Great Quality, Lower Cost

Keeping a tablet press operating at peak performance with as little downtime as possible is important for any tablet manufacturer. But for many, keeping maintenance costs within reason is equally important. Although parts sourced through an Original Equipment Manufacturer (OEM) or authorized OEM dealer may sound initially appealing, there are several things to consider before… Read More

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The training, factory staff and instruction completely exceeded all expectations. I would come back anytime; easily one of the Top 10, if not Top 5, companies I have visited with. I spoke with Dale about what a great company Natoli is.

- Animal Health Company