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Solid Dose, It's In Natoli DNA

Natoli Engineering is the global leader in tablet compression tooling manufacturing. For the last half a century Natoli has been a fully encompassing solutions provider in the oral solid dose industry helping clients establish processes to achieve the perfect tablets and capsules.


Founded on the uncompromising principle of providing the highest quality products allows Natoli to deliver world class tablet compression tooling, best-in-class presses, encapsulation machines, and replacement parts with exceptional global support.


Natoli’s continued innovation and industry leadership, state-of-the-art manufacturing facilities, award-winning engineering team gives Natoli the capabilities to meet any industry demand.


Tablet Compression Tooling

Natoli manufactures carbide-tip, multi-tip, single-tip, 3D exotic shape, rotating heads/tips, and extended head flat punches, plus lined dies, tool coatings, and IMA Comprima tooling.

Tablet Presses

Natoli offers a diverse line of best-in class tablet press options, from single station R&D laboratory models to robust large-scale manufacturing rotary presses.

Natoli Scientific

Natoli Scientific advanced laboratories and team of highly qualified pharmaceutical scientist provide formulation evaluations, training, contract research, and consulting services.

Encapsulation Change and Spare Parts

Natoli offers premium Encapsulation Machine spare parts, change parts, and change kits for most major brands.

Encapsulation Machines

The Natoli NCF-45 Automatic Encapsulation Machine. This machine produces 45,000 capsules per hour.

Technical Training

Natoli offers complete hands-on instruction. The knowledge and expertise Natoli has gathered over 50 years in the tablet compression tooling industry is packaged into our training courses.

Tablet Press Replacement Parts

Natoli maintains an extensive inventory of replacement parts for tablet press and encapsulation machines for use with most major brands.

Tablet Compression Accessories

Natoli offers the most comprehensive accessories catalog in the industry, featuring items to help maintain, analyze, and prolong the life of tooling and equipment.

Natoli AIM Data Acquisition and Analytical Software

Natoli AIM Analytical and Control System Software is engineered for R&D and production tablet presses, encapsulation machines, high shear granulators, and roller compactors.


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- a Pharmaceutical Company