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Make Quick Work of Tablet R&D

For use with R&D tablet presses, Natoli Quick-Release™ Tooling allows researchers to quickly change punch head configurations to determine the ideal dwell time for a tablet formulation.


  • One punch barrel
  • Three interchangeable head configurations (domed, extended flat domed, and full radius)
  • One customized punch tip

Solve tableting scale-up challenges while saving both time and money with innovative Quick-Release™ Tooling

  • Determine the ideal production dwell time before scale-up without changing turret speed by easily and quickly changing punch head configurations
  • Eliminate the time and labor required to replace multiple sets of tooling during the R&D process and the cost of purchasing multiple sets of tooling
  • Perform a detailed analysis of a formulation’s compressibility as well as greater troubleshooting capacity in the early stages of tablet development


Solve Formulation Challenges Before Scale-up

Scaling up a tablet to manufacturing production can be difficult due to mechanical and operational differences between R&D and production tablet presses. Natoli Quick-Release™ Tooling helps resolve these concerns in the development stage, allowing the researcher to:

  • Quickly and easily change punch head configurations to test different dwell times without purchasing multiple sets of tooling or changing turret speed
  • Determine the ideal compression profile while keeping the turret at the required speed relative to powder feed and desired tablet output—invaluable for continuous manufacturing
  • Optimize material selection for each punch component


Ceramic Barrel Option:

  • Requires no lubrication
  • Less wear, less friction, and less heat buildup
  • Absorbs less heat from surrounding metals
  • Will not expand due to heat
  • Reduces potential for tooling binding



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Natoli has ensured that our operations are running on the cutting edge with the latest methods and improvements in the industry. I appreciate the staff’s continuous customer service and support long after our initial purchases with them. I also appreciate the effective communication for inquires that happen frequently for me, a rare quality to find these days. The Natoli team is quite knowledgeable and the best in the business!

- Manufacturing Technician Lead atSterisil, Inc